Myths and Facts - Nicotine Addiction and Genetics

Over the past few decades, an increasing numbervariants are not enough to develop addiction.
of individuals ranging from minors to teenagersMyth: " Nicotine addiction is hereditary in nature."
including adults are engaging into the habit ofFact: The nicotinic receptor gene variants may be
smoking. As a result, more people arehereditary however, addiction only results from
experiencing the addictive effect of nicotine. Sincethe activation of such genes through an external
it is actually highly addictive, frequent smokersfactor. This implies that an environmental factor
eventually develop nicotine addiction frommay cancel out an addiction gene resulting to its
cigarettes. In response, the US government fundsinactivated state. Thus, the children may have the
genetic researchers to continuously study geneticgene but they can always fight it off by not
links between nicotine addiction and first timetrying smoking in the first place.
smokers and create probable smoking cessationMyth: " An unpleasant first smoking experience will
methods using these newly discovered addictionnot make you vulnerable to nicotine addiction."
genetic markers.Fact: While for most of the people who
Genetics of Nicotine Addiction Myths VS Factsexperience something unpleasant tends to avoid
Recently, reports of breakthroughs about nicotineit, circumstances for habitual smoking are quite
addiction and its relation to genetics aredifferent. A recent finding regarding nicotine is that
proliferating online. With all these informationa first time encounter seems to suggest intensity,
available, it is hard to pinpoint which are true andrather that pleasure. The shocking results
which are not. It is even harder to determineconfirmed that most people who undergone
whether these claims are real due to the factunpleasant first smoking encounters were the
that most of them are merely assumptions andones who developed nicotine addiction.
still need further investigations. Anyway, to fullyMyth: "Presence of nicotinic receptor genes is the
understand about the genetics of addiction, hereroot cause of obsession to cigarette smoking."
are some misconceptions that should not beFact: While it might be true that triggering these
confuse with already established facts.nicotinic receptor gene variants may increase the
Myth: " Nicotine addiction is inevitable for nicotinicchances of developing addiction, an individual's
receptor gene variant carriers."environment still plays a big part of it. Peer
Fact: While it is true that carrying a nicotinicpressure, depression, stress and other external
receptor gene variant makes an individualfactors also help in urging the person to smoke
vulnerable to addiction, susceptibility does notwhich will eventually lead to nicotine addiction.
mean inevitability. It is not always certain thatNonetheless, whether targeting these nicotinic
carrying a receptor gene will make a smokerreceptor gene variants may lessen if not prevent
exhibit addictive traits. Carriers should just avoidcases of addiction, it is still a positive breakthrough
activating these genes or the best thing to do isin the field of science. Identifying such genes may
not to try smoking as much possible.prove to be helpful for future creation of possible
Myth: " Only one type of nicotinic receptor gene iscessation methods for cigarette smoking. By
all it takes to become susceptible to nicotineidentifying specific nicotinic receptor genes
addiction."responsible for addiction, scientists may uncover
Fact: Susceptibility to nicotine addiction requiresprobable medications for addiction treatment.
interaction of various receptor gene variants. EvenWhether the reality of genetics being responsible
a recent research study supports that out offor addiction is true or not, what is important is
30,000 genes in the body, 594 are morerealizing the fact that there are some reasons
activated and 584 are less activated in genes ofbehind the cause of nicotine addiction that is
smokers compared to non-smokers. It clearlybeyond our control.
shows that even 2 or 3 nicotinic receptor gene